• Wholesale Galanthamine Hydrobromide(Lycoris P.E.)98%/Galanthamine HBr, 100gram/bag

Galanthamine Hydrobromide(Lycoris P.E.)98%/Galanthamine HBr, 100gram/bag

  • item#: 257
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  • Wholesale Price: 1950.00

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      Product Details

      Galanthamine Hydrobromide(Lycoris P.E.)98%/Galanthamine HBr, 100gram/bag

       

      Product Name: Galanthamine Hydrobromide

      Original Plant: Shorttube Lycoris

      Appearance: White to whitish crystal powder

      Specification: 99%min.

      Synonym(s): Reminyl, Nivalin

      Chemical name:(4aS,6R,8aS)-6-Hydroxy-3-methoxy-11-methyl-5,6,9,10,11,12-hexahydro-4aH-benzofuro[3a,3,2-e,f][2]benzazepine hydrobromide

      Test Method: HPLC

      Molecular Formula: C17H21NO3.HBr;C17H22BrNO3

      Molecular Weight: 368.27

      CAS No.:1953-04-4

      Packing size: 100gram/bag, 500gram/carton, 25 kg/barrel or according to the customer request

       

      Pharmacology Action: Galanthamine extract is specific, competitive and reversible acetylcholinesterase inhibitor. It is also an allosteric modulator at nicotinic cholinergic receptor sites potentiating cholinergic nicotinic neurotransmission. Both the acetylcholine and nicotine receptors have been suggested as areas related to cognitive impairment. Initially, Galanthamine extract was used in anesthesiology to antagonize the effects of non-depolarizing muscle relaxants, and since then it was rapidly introduced in other areas of medicine, i.e. neurology, ophthalmology, gastroenterology, intensive care and resuscitation, cardiology, physiotherapy. Several trials already showed that Galantamine 16 and 24 mg/day significantly benefits the cognitive, functional, and behavioral symptoms of AD as compared with placebo and proved also to be very effective in symptomatic treatment of senile dementia of Alzheimer's type

      Product introduction:

      Galanthamine is natural extracted from lycoris radiate, is a tertiary alkaloid derived from snow drop and closely related species. It acts as a reversible competitive acetylcholinesterase (ACHE) inhibitor, while acts weaker on butyrylcholinesterse(BuChE).it is used in the treatment of disorders of the central nervous system and may be used as an antidote to nonpolarizing muscle relaxants. Galanthamine hydrobromide is a white to almost white powder; sparingly soluble in water; insoluble chloroform, ether and alcohol.

       


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